Page counts up to 400 pages can be done with Perfect Binding, but extra caution is needed for such high numbers of pages. This is due to the structure of the binding and the fact that the book should not be opened too far, or there is a risk of breaking the spine. Therefore a book with smaller dimensions might not have enough space for sufficient margins to keep the content far away enough from the spine gutter.

If a thick book is desired and/or the application requires the book to open wide and lay flat on a table, there is a specific type of perfect binding called "lay flat" binding that, as the name suggests, would allow this without risking the spine breaking. This is not the standard for perfect binding as there are additional operations required, so if this is needed, then a custom estimate would be required.